超清版 GB/T 44366-2024 化妆品中限用组分月桂醇聚醚-9的测定 液相色谱-串联质谱法
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资料介绍
ICS 71.100.70
CCS Y 42
中华人民共和国国家标准
GB/T 44366—2024
化妆品中限用组分月桂醇聚醚-9 的
测定 液相色谱-串联质谱法
Determination of restricted lauryl alcohol polyether-9 in cosmetics—
Liquid chromatography tandem mass spectrometry
2024-08-23 发布2025-03-01 实施
国家市场监督管理总局
国家标准化管理委员会发 布
目 次
前言 ····································································································· Ⅲ
1 范围 ·································································································· 1
2 规范性引用文件 ······················································································ 1
3 术语和定义 ··························································································· 1
4 原理 ·································································································· 1
5 试剂和材料 ··························································································· 1
6 仪器设备 ······························································································ 2
7 试样制备和试验步骤 ················································································· 2
7.1 试样制备 ························································································· 2
7.2 液相色谱参考条件 ··············································································· 2
7.3 质谱参考条件 ···················································································· 2
7.4 标准工作曲线绘制 ··············································································· 3
7.5 定性确证 ························································································· 3
7.6 定量分析 ························································································· 3
7.7 空白试验 ························································································· 3
8 试验数据处理 ························································································· 3
9 回收率 ································································································ 4
10 精密度 ······························································································· 4
附录A （资料性） 月桂醇聚醚﹘9 标准物质的信息 ···················································· 5
附录B （资料性） 月桂醇聚醚﹘9 选择离子MRM 色谱图 ············································· 6
前 言
本文件按照GB/T 1.1—2020《标准化工作导则 第1 部分：标准化文件的结构和起草规则》的规
定起草。
请注意本文件的某些内容可能涉及专利。本文件的发布机构不承担识别专利的责任。
本文件由轻工业联合会提出。
本文件由全国香料香精化妆品标准化技术委员会（SAC/TC 257）归口。
本文件起草单位：上海海关动植物与食品检验检疫技术中心、南京师范大学、上海家化联合股份有
限公司、鲅鱼圈海关综合技术服务中心。
本文件主要起草人：王粮子、赵波、王传现、杨振宇、陈念念、蒋珍娟、李涛、林天闻、陈志涛、
韩丽、顾杨。
1 范围
本文件描述了化妆品中月桂醇聚醚﹘9 的液相色谱﹘串联质谱测定方法的原理、试剂和材料、仪器设
备、试样制备和试验步骤、试验数据处理、回收率和精密度等内容。
本文件适用于水剂类、膏霜类、乳液类、洗护类等化妆品中月桂醇聚醚﹘9 含量的测定。
本文件方法检出限为1.0 mg/kg，定量限为10.0 mg/kg。
2 规范性引用文件
下列文件中的内容通过文中的规范性引用而构成本文件必不可少的条款。其中，注日期的引用文
件，仅该日期对应的
CCS Y 42
中华人民共和国国家标准
GB/T 44366—2024
化妆品中限用组分月桂醇聚醚-9 的
测定 液相色谱-串联质谱法
Determination of restricted lauryl alcohol polyether-9 in cosmetics—
Liquid chromatography tandem mass spectrometry
2024-08-23 发布2025-03-01 实施
国家市场监督管理总局
国家标准化管理委员会发 布
目 次
前言 ····································································································· Ⅲ
1 范围 ·································································································· 1
2 规范性引用文件 ······················································································ 1
3 术语和定义 ··························································································· 1
4 原理 ·································································································· 1
5 试剂和材料 ··························································································· 1
6 仪器设备 ······························································································ 2
7 试样制备和试验步骤 ················································································· 2
7.1 试样制备 ························································································· 2
7.2 液相色谱参考条件 ··············································································· 2
7.3 质谱参考条件 ···················································································· 2
7.4 标准工作曲线绘制 ··············································································· 3
7.5 定性确证 ························································································· 3
7.6 定量分析 ························································································· 3
7.7 空白试验 ························································································· 3
8 试验数据处理 ························································································· 3
9 回收率 ································································································ 4
10 精密度 ······························································································· 4
附录A （资料性） 月桂醇聚醚﹘9 标准物质的信息 ···················································· 5
附录B （资料性） 月桂醇聚醚﹘9 选择离子MRM 色谱图 ············································· 6
前 言
本文件按照GB/T 1.1—2020《标准化工作导则 第1 部分：标准化文件的结构和起草规则》的规
定起草。
请注意本文件的某些内容可能涉及专利。本文件的发布机构不承担识别专利的责任。
本文件由轻工业联合会提出。
本文件由全国香料香精化妆品标准化技术委员会（SAC/TC 257）归口。
本文件起草单位：上海海关动植物与食品检验检疫技术中心、南京师范大学、上海家化联合股份有
限公司、鲅鱼圈海关综合技术服务中心。
本文件主要起草人：王粮子、赵波、王传现、杨振宇、陈念念、蒋珍娟、李涛、林天闻、陈志涛、
韩丽、顾杨。
1 范围
本文件描述了化妆品中月桂醇聚醚﹘9 的液相色谱﹘串联质谱测定方法的原理、试剂和材料、仪器设
备、试样制备和试验步骤、试验数据处理、回收率和精密度等内容。
本文件适用于水剂类、膏霜类、乳液类、洗护类等化妆品中月桂醇聚醚﹘9 含量的测定。
本文件方法检出限为1.0 mg/kg，定量限为10.0 mg/kg。
2 规范性引用文件
下列文件中的内容通过文中的规范性引用而构成本文件必不可少的条款。其中，注日期的引用文
件，仅该日期对应的